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Sodium correction for hyperglycemia

A high glucose pulls water into the vascular space and dilutes sodium, so the measured sodium understates the true value. This gives the sodium you would expect once the glucose is normal.

Enter the values

mEq/L
mg/dL

Hillier fits better at glucose above roughly 400 mg/dL.

The result appears as you type.

Nothing is sent anywhere. The calculation runs entirely in your browser.

This calculator is provided for reference and education. It does not replace clinical assessment, examination, current guidelines, local protocol, or professional judgment. Verify every result before acting on it. Nirogix accepts no liability for clinical decisions made using this tool.

The formula

  • Katz: corrected Na = measured Na + 1.6 × (glucose − 100) ÷ 100
  • Hillier: corrected Na = measured Na + 2.4 × (glucose − 100) ÷ 100

Worked example

Sodium 128 with glucose 600 mg/dL (Katz) → 128 + 1.6 × 5 = 136 mEq/L

When to use it

  • Diabetic ketoacidosis and hyperosmolar hyperglycemic state
  • Any hyponatremia with a markedly raised glucose

And when not to

  • Correction rate matters more than the correction: over-rapid correction of chronic hyponatremia risks osmotic demyelination.
  • Severe hypertriglyceridemia and paraproteinemia cause a different artefact this does not address.

References

  • Hyperglycemia-induced hyponatremiaKatz MA, New England Journal of Medicine, 1973
  • Hyponatremia: evaluating the correction factor for hyperglycemiaHillier TA et al., American Journal of Medicine, 1999

Last reviewed 07/09/2026.

These calculators are free and always will be. We also build Nirogix, a hospital management system for Indian clinics and hospitals. The same calculations are planned inside the consultation record, pre-filled from the chart.