Cardiology
Framingham 10-year cardiovascular risk
This estimates the chance of a first cardiovascular event, whether coronary, cerebrovascular, peripheral arterial or heart failure, in the next ten years, from the 2008 general Framingham risk profile. It is an estimate for a person without established cardiovascular disease.
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This calculator is provided for reference and education. It does not replace clinical assessment, examination, current guidelines, local protocol, or professional judgment. Verify every result before acting on it. Nirogix accepts no liability for clinical decisions made using this tool.
The formula
- Sex-specific Cox model: risk = 1 − S₀^exp(Σβx − mean)
- Predictors: ln(age), ln(total cholesterol), ln(HDL), ln(systolic BP, with a separate coefficient if treated), smoking, diabetes
- Men: S₀ = 0.88936, mean = 23.9802 · Women: S₀ = 0.95012, mean = 26.1931
When to use it
- Primary prevention risk assessment in an adult aged 30 to 74 without established cardiovascular disease
And when not to
- Derived in a white American cohort. It under-estimates risk in South Asians, which matters directly here.
- It is a primary prevention tool. It does not apply to someone who already has cardiovascular disease.
- Validated for ages 30 to 74; outside that range it should not be used.
References
- General cardiovascular risk profile for use in primary care — D'Agostino RB et al., Circulation, 2008
Last reviewed 07/09/2026.
Derived from a non-Indian cohort. The page must keep saying so; if an Indian-validated equation becomes standard, this is replaced rather than supplemented.
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These calculators are free and always will be. We also build Nirogix, a hospital management system for Indian clinics and hospitals. The same calculations are planned inside the consultation record, pre-filled from the chart.